7UI0
Post-fusion ectodomain of HSV-1 gB in complex with HSV010-13 Fab
This is a non-PDB format compatible entry.
Summary for 7UI0
Entry DOI | 10.2210/pdb7ui0/pdb |
EMDB information | 26521 |
Descriptor | Envelope glycoprotein B, HSV10-13 Fab Heavy chain, HSV10-13 Light chain (3 entities in total) |
Functional Keywords | glycoprotein, fusogen, antibody, adcc, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human alphaherpesvirus 1 strain KOS More |
Total number of polymer chains | 9 |
Total formula weight | 289793.96 |
Authors | Windsor, I.W.,Kong, S.L.,Garforth, S.J.,Almo, S.C.,Harrison, S.C. (deposition date: 2022-03-28, release date: 2023-02-08, Last modification date: 2023-02-15) |
Primary citation | Kuraoka, M.,Aschner, C.B.,Windsor, I.W.,Mahant, A.M.,Garforth, S.J.,Kong, S.L.,Achkar, J.M.,Almo, S.C.,Kelsoe, G.,Herold, B.C. A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice. J.Clin.Invest., 133:-, 2023 Cited by PubMed: 36454639DOI: 10.1172/JCI161968 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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