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7UGE

Bromodomain of CBP liganded with BMS-536924

Summary for 7UGE
Entry DOI10.2210/pdb7uge/pdb
DescriptorHistone acetyltransferase, (3M)-4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-3-[4-methyl-6-(morpholin-4-yl)-1H-benzimidazol-2-yl]pyridin-2(1H)-one, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsbromodomain, small molecule ligand, complex, transcription
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight28717.75
Authors
Schonbrunn, E.,Bikowitz, M. (deposition date: 2022-03-24, release date: 2023-04-12, Last modification date: 2023-10-25)
Primary citationSchonbrunn, E.,Bikowitz, M.
Structural basis of CBP and EP300 interaction with kinase inhibitors
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.004 Å)
Structure validation

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PDB entries from 2024-11-06

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