7UG5

Second bromodomain of BRD3 liganded with BMS-536924

Summary for 7UG5

• Entry DOI: 10.2210/pdb7ug5/pdb
• Descriptor: Bromodomain-containing protein 3, (3M)-4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-3-[4-methyl-6-(morpholin-4-yl)-1H-benzimidazol-2-yl]pyridin-2(1H)-one, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: bromodomain, small molecule ligand, complex, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 54309.51

Authors

Schonbrunn, E.,Bikowitz, M. (deposition date: 2022-03-23, release date: 2023-04-05, Last modification date: 2023-10-25)

• Primary citation: Schonbrunn, E.,Bikowitz, M.; Structural basis of CBP and EP300 interaction with kinase inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)