7UEX

PANK3 complex structure with compound PZ-4127

7UEX の概要

• エントリーDOI: 10.2210/pdb7uex/pdb
• 分子名称: Pantothenate kinase 3, ACETATE ION, 2-(4-{2-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}anilino)-2-oxoethyl acetate, ... (8 entities in total)
• 機能のキーワード: pank, transferase, inhibitor, activator, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43306.76

構造登録者

White, S.W.,Yun, M.,Lee, R.E. (登録日: 2022-03-22, 公開日: 2023-03-29, 最終更新日: 2023-10-25)

• 主引用文献: Tangallapally, R.,Edwards, A.,Subramanian, C.,Sharma, L.K.,Yun, M.,White, S.W.,Jackowski, S.,Rock, C.O.,Lee, R.E.; Discovery of hPANK Activators with Improved Pharmacological Properties; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)