7UA7
Crystal structure of indoline 9 with KPC-2
Summary for 7UA7
Entry DOI | 10.2210/pdb7ua7/pdb |
Descriptor | Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL, tert-butyl {(3R)-3-[(1H-tetrazol-5-yl)carbamoyl]-1-[3-(trifluoromethyl)benzoyl]-2,3-dihydro-1H-indol-3-yl}carbamate, ... (4 entities in total) |
Functional Keywords | beta-lactamase, tetrazole, inhibitor, complex, hydrolase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 29583.16 |
Authors | Akhtar, A.,Chen, Y. (deposition date: 2022-03-11, release date: 2023-03-15, Last modification date: 2023-10-25) |
Primary citation | DeFrees, K.,Cambeis, E.M.,Chen, Y.,Renslo, A.R. Probing the binding hot spots of KPC-2 carbapenemase using reversible tetrazole-based inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.247 Å) |
Structure validation
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