7UA7

Crystal structure of indoline 9 with KPC-2

Summary for 7UA7

• Entry DOI: 10.2210/pdb7ua7/pdb
• Descriptor: Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL, tert-butyl {(3R)-3-[(1H-tetrazol-5-yl)carbamoyl]-1-[3-(trifluoromethyl)benzoyl]-2,3-dihydro-1H-indol-3-yl}carbamate, ... (4 entities in total)
• Functional Keywords: beta-lactamase, tetrazole, inhibitor, complex, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 29583.16

Authors

Akhtar, A.,Chen, Y. (deposition date: 2022-03-11, release date: 2023-03-15, Last modification date: 2024-11-20)

• Primary citation: DeFrees, K.,Cambeis, E.M.,Chen, Y.,Renslo, A.R.; Probing the binding hot spots of KPC-2 carbapenemase using reversible tetrazole-based inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.247 Å)