7U8M
Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibodies 31.a.83 and FluA-20
Summary for 7U8M
Entry DOI | 10.2210/pdb7u8m/pdb |
Related | 7U8L |
Descriptor | hemagglutinin HA1 subunit, hemagglutinin HA2 subunit, Antibody 31.a.83 Fab light chain, ... (6 entities in total) |
Functional Keywords | universal vaccine design, chimeric influenza hemagglutinin, ha trimer interface and stem, viral protein-immune system complex, viral protein/immune system |
Biological source | Influenza A virus More |
Total number of polymer chains | 18 |
Total formula weight | 458957.24 |
Authors | Zhu, X.,Wilson, I.A. (deposition date: 2022-03-08, release date: 2022-06-08, Last modification date: 2023-10-18) |
Primary citation | Zhu, X.,Han, J.,Sun, W.,Puente-Massaguer, E.,Yu, W.,Palese, P.,Krammer, F.,Ward, A.B.,Wilson, I.A. Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface. Proc.Natl.Acad.Sci.USA, 119:e2200821119-e2200821119, 2022 Cited by PubMed: 35594401DOI: 10.1073/pnas.2200821119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (5.39 Å) |
Structure validation
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