7U8E
Crystal structure of antibody Ab246 in complex with SARS-CoV-2 receptor binding domain
Summary for 7U8E
Entry DOI | 10.2210/pdb7u8e/pdb |
Descriptor | Spike protein S1, Antibody Ab246 Fab heavy chain, Antibody Ab246 Fab light chain, ... (7 entities in total) |
Functional Keywords | neutralizing antibody, sars-cov-2, ab246, receptor binding domain, antiviral protein, viral protein-immune system complex, viral protein, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 3 |
Total formula weight | 71663.40 |
Authors | Sankhala, R.S.,Joyce, M.G. (deposition date: 2022-03-08, release date: 2023-03-15, Last modification date: 2024-02-14) |
Primary citation | Sankhala, R.S.,Dussupt, V.,Chen, W.H.,Bai, H.,Martinez, E.J.,Jensen, J.L.,Rees, P.A.,Hajduczki, A.,Chang, W.C.,Choe, M.,Yan, L.,Sterling, S.L.,Swafford, I.,Kuklis, C.,Soman, S.,King, J.,Corbitt, C.,Zemil, M.,Peterson, C.E.,Mendez-Rivera, L.,Townsley, S.M.,Donofrio, G.C.,Lal, K.G.,Tran, U.,Green, E.C.,Smith, C.,de Val, N.,Laing, E.D.,Broder, C.C.,Currier, J.R.,Gromowski, G.D.,Wieczorek, L.,Rolland, M.,Paquin-Proulx, D.,van Dyk, D.,Britton, Z.,Rajan, S.,Loo, Y.M.,McTamney, P.M.,Esser, M.T.,Polonis, V.R.,Michael, N.L.,Krebs, S.J.,Modjarrad, K.,Joyce, M.G. Antibody targeting of conserved sites of vulnerability on the SARS-CoV-2 spike receptor-binding domain. Structure, 32:131-147.e7, 2024 Cited by PubMed: 38157856DOI: 10.1016/j.str.2023.11.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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