7U70

Crystal Structure of CTX-M-14 with compound 2

Summary for 7U70

• Entry DOI: 10.2210/pdb7u70/pdb
• Descriptor: Beta-lactamase, 3-fluoro-N-[(1R,3S)-3-(1H-tetrazol-5-yl)-2,3-dihydro-1H-inden-1-yl]benzamide (3 entities in total)
• Functional Keywords: beta-lactamase, tetrazole, inhibitor, complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 56647.74

Authors

Akhtar, A.,Chen, Y. (deposition date: 2022-03-07, release date: 2023-03-22, Last modification date: 2023-10-25)

• Primary citation: DeFrees, K.,Cambeis, E.M.,Chen, Y.,Renslo, A.R.; Probing the binding hot spots of KPC-2 carbapenemase using reversible tetrazole-based inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.36 Å)