7U64

Crystal Structure of Anti-Fentanyl Antibody HY6-F9.6 Fab Complexed with Fentanyl

Summary for 7U64

Entry DOI	10.2210/pdb7u64/pdb
Descriptor	HY6-F9.6 Fab heavy chain, HY6-F9.6 Fab light chain, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide, ... (6 entities in total)
Functional Keywords	mab, opioid, immune system
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	18
Total formula weight	441946.41
Authors	Rodarte, J.V.,Pancera, M.P. (deposition date: 2022-03-03, release date: 2023-01-11, Last modification date: 2023-10-25)
Primary citation	Rodarte, J.V.,Baehr, C.,Hicks, D.,Liban, T.L.,Weidle, C.,Rupert, P.B.,Jahan, R.,Wall, A.,McGuire, A.T.,Strong, R.K.,Runyon, S.,Pravetoni, M.,Pancera, M. Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding. Structure, 31:20-32.e5, 2023 Cited by PubMed: 36513069 DOI: 10.1016/j.str.2022.11.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation