7U5C
Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state
Summary for 7U5C
Entry DOI | 10.2210/pdb7u5c/pdb |
EMDB information | 26346 |
Descriptor | DNA primase small subunit, IRON/SULFUR CLUSTER, DNA primase large subunit, ... (10 entities in total) |
Functional Keywords | fill-in, telomere, replication, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 502115.02 |
Authors | Cai, S.W.,Zinder, J.C.,Svetlov, V.,Bush, M.W.,Nudler, E.,Walz, T.,de Lange, T. (deposition date: 2022-03-02, release date: 2022-05-18, Last modification date: 2024-02-14) |
Primary citation | Cai, S.W.,Zinder, J.C.,Svetlov, V.,Bush, M.W.,Nudler, E.,Walz, T.,de Lange, T. Cryo-EM structure of the human CST-Pol alpha /primase complex in a recruitment state. Nat.Struct.Mol.Biol., 29:813-819, 2022 Cited by PubMed: 35578024DOI: 10.1038/s41594-022-00766-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.6 Å) |
Structure validation
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