7U4W

The ubiquitin-associated domain of human thirty-eight negative kinase-1 flexibly fused to the 1TEL crystallization chaperone via a 2-glycine linker and crystallized at traditional protein concentration

7U4W の概要

• エントリーDOI: 10.2210/pdb7u4w/pdb
• 関連するPDBエントリー: 7T8J 7TCY 7TDY
• 分子名称: Transcription factor ETV6,Non-receptor tyrosine-protein kinase TNK1 (2 entities in total)
• 機能のキーワード: protein polymer, ubiquitin-associated domain, helix bundle, chimera, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17775.05

構造登録者

Nawarathnage, S.,Pedroza Romo, M.J.,Smith, T.,Bunn, D.,Stewart, C.,Doukov, T.,Moody, J.D. (登録日: 2022-03-01, 公開日: 2023-03-08, 最終更新日: 2023-12-20)

• 主引用文献: Nawarathnage, S.,Tseng, Y.J.,Soleimani, S.,Smith, T.,Pedroza Romo, M.J.,Abiodun, W.O.,Egbert, C.M.,Madhusanka, D.,Bunn, D.,Woods, B.,Tsubaki, E.,Stewart, C.,Brown, S.,Doukov, T.,Andersen, J.L.,Moody, J.D.; Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain.; Structure, 31:1589-, 2023; PubMed: 37776857; DOI: 10.1016/j.str.2023.09.001

実験手法

X-RAY DIFFRACTION (2.1 Å)