7U3D

Structure of S. venezuelae GlgX-c-di-GMP-acarbose complex (4.6)

7U3D の概要

• エントリーDOI: 10.2210/pdb7u3d/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900007
• 分子名称: Glycogen debranching enzyme GlgX, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ... (4 entities in total)
• 機能のキーワード: glgx, glycogen, c-di-gmp, acarbose, streptomyces development, hydrolase
• 由来する生物種: Streptomyces venezuelae
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 326013.00

構造登録者

Schumacher, M.A. (登録日: 2022-02-27, 公開日: 2022-10-05, 最終更新日: 2023-10-18)

• 主引用文献: Schumacher, M.A.,Wormann, M.E.,Henderson, M.,Salinas, R.,Latoscha, A.,Al-Bassam, M.M.,Singh, K.S.,Barclay, E.,Gunka, K.,Tschowri, N.; Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP.; Nat Commun, 13:5834-5834, 2022; PubMed: 36192422; DOI: 10.1038/s41467-022-33537-w

実験手法

X-RAY DIFFRACTION (2.4 Å)