7U3B
Structure of S. venezuelae GlgX bound to c-di-GMP and acarbose (pH 8.5)
Summary for 7U3B
Entry DOI | 10.2210/pdb7u3b/pdb |
Descriptor | Glycogen debranching enzyme GlgX, 4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranosyl)-beta-D-glucopyranose, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ... (5 entities in total) |
Functional Keywords | glgx, glycogen, acarbose, c-di-gmp, streptomyces, hydrolase |
Biological source | Streptomyces venezuelae |
Total number of polymer chains | 8 |
Total formula weight | 651124.88 |
Authors | Schumacher, M.A.,Tschowri, N. (deposition date: 2022-02-26, release date: 2022-10-05, Last modification date: 2023-10-18) |
Primary citation | Schumacher, M.A.,Wormann, M.E.,Henderson, M.,Salinas, R.,Latoscha, A.,Al-Bassam, M.M.,Singh, K.S.,Barclay, E.,Gunka, K.,Tschowri, N. Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP. Nat Commun, 13:5834-5834, 2022 Cited by PubMed: 36192422DOI: 10.1038/s41467-022-33537-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
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