7U0M
Crystal structure of a enoyl-[acyl-carrier-protein] reductase (InhA) from Mycobacterium abscessus bound to NAD and NITD-916
7U0M の概要
エントリーDOI | 10.2210/pdb7u0m/pdb |
分子名称 | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 6-[(4,4-dimethylcyclohexyl)methyl]-4-hydroxy-3-phenylpyridin-2(1H)-one, ... (5 entities in total) |
機能のキーワード | inha, mycobacterium, tuberculosis, cystic fibrosis, cf, pulmonary infections, structural genomics, seattle structural genomics center for infectious disease, ssgcid, oxidoreductase |
由来する生物種 | Mycobacteroides abscessus |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 61385.81 |
構造登録者 | Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2022-02-18, 公開日: 2022-10-05, 最終更新日: 2023-10-18) |
主引用文献 | Alcaraz, M.,Roquet-Baneres, F.,Leon-Icaza, S.A.,Abendroth, J.,Boudehen, Y.M.,Cougoule, C.,Edwards, T.E.,Kremer, L. Efficacy and Mode of Action of a Direct Inhibitor of Mycobacterium abscessus InhA. Acs Infect Dis., 8:2171-2186, 2022 Cited by PubMed: 36107992DOI: 10.1021/acsinfecdis.2c00314 主引用文献が同じPDBエントリー |
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