7TXB

Structure of the Class II Fructose-1,6-Bisphophatase from Mycobacterium tuberculosis complexed with substrate F1,6BP

Summary for 7TXB

Entry DOI	10.2210/pdb7txb/pdb
Descriptor	Fructose-1,6-bisphosphatase class 2, GLYCEROL, 1,6-di-O-phosphono-beta-D-fructofuranose, ... (5 entities in total)
Functional Keywords	class ii fbpases; fructose-1, 6-bisphosphatase; francisella tularensis; mycobacterium tuberculosis; gluconeogenesis; antibiotic targets, hydrolase, hydrolase-substrate complex, hydrolase/substrate
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	74233.89
Authors	Abad-Zapatero, C.,Selezneva, A.I.,Gutka, H.J. (deposition date: 2022-02-08, release date: 2023-06-28, Last modification date: 2023-10-25)
Primary citation	Selezneva, A.I.,Harding, L.N.M.,Gutka, H.J.,Movahedzadeh, F.,Abad-Zapatero, C. New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class. Plos One, 18:e0274723-e0274723, 2023 Cited by PubMed: 37352301 DOI: 10.1371/journal.pone.0274723 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.71 Å)

Structure validation