7TXA
Structure of the Class II Fructose-1,6-Bisphophatase from Francisella tularensis complexed with native metal cofactor Mn++ and product F6P
Summary for 7TXA
Entry DOI | 10.2210/pdb7txa/pdb |
Descriptor | Fructose-1,6-bisphosphatase, MANGANESE (II) ION, 6-O-phosphono-beta-D-fructofuranose, ... (4 entities in total) |
Functional Keywords | class ii fbpases; fructose-1, 6-bisphosphatase; francisella tularensis; mycobacterium tuberculosis; gluconeogenesis; antibiotic targets, hydrolase, hydrolase-product complex, hydrolase/product |
Biological source | Francisella tularensis |
Total number of polymer chains | 8 |
Total formula weight | 297349.09 |
Authors | Abad-Zapatero, C.,Selezneva, A.I. (deposition date: 2022-02-08, release date: 2023-06-28, Last modification date: 2023-10-25) |
Primary citation | Selezneva, A.I.,Harding, L.N.M.,Gutka, H.J.,Movahedzadeh, F.,Abad-Zapatero, C. New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class. Plos One, 18:e0274723-e0274723, 2023 Cited by PubMed: 37352301DOI: 10.1371/journal.pone.0274723 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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