7TXA

Structure of the Class II Fructose-1,6-Bisphophatase from Francisella tularensis complexed with native metal cofactor Mn++ and product F6P

Summary for 7TXA

Entry DOI	10.2210/pdb7txa/pdb
Descriptor	Fructose-1,6-bisphosphatase, MANGANESE (II) ION, 6-O-phosphono-beta-D-fructofuranose, ... (4 entities in total)
Functional Keywords	class ii fbpases; fructose-1, 6-bisphosphatase; francisella tularensis; mycobacterium tuberculosis; gluconeogenesis; antibiotic targets, hydrolase, hydrolase-product complex, hydrolase/product
Biological source	Francisella tularensis
Total number of polymer chains	8
Total formula weight	297349.09
Authors	Abad-Zapatero, C.,Selezneva, A.I. (deposition date: 2022-02-08, release date: 2023-06-28, Last modification date: 2023-10-25)
Primary citation	Selezneva, A.I.,Harding, L.N.M.,Gutka, H.J.,Movahedzadeh, F.,Abad-Zapatero, C. New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class. Plos One, 18:e0274723-e0274723, 2023 Cited by PubMed: 37352301 DOI: 10.1371/journal.pone.0274723 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation