7TVS

The Crystal Structure of SARS-CoV-2 Omicron Mpro (P132H) in complex with demethylated analog of masitinib

Summary for 7TVS

• Entry DOI: 10.2210/pdb7tvs/pdb
• Descriptor: 3C-like proteinase nsp5, N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)-4-[(piperazin-1-yl)methyl]benzamide, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: sars-cov-2, omicron, 3cl, masitinib, structural genomics, center for structural genomics of infectious diseases, csgid, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus
• Total number of polymer chains: 1
• Total formula weight: 34507.46

Authors

Tan, K.,Maltseva, N.I.,Endres, M.J.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2022-02-05, release date: 2022-02-16, Last modification date: 2023-10-18)

• Primary citation: Tan, K.,Maltseva, N.I.,Endres, M.J.,Joachimiak, A.; The Crystal Structure of SARS-CoV-2 Omicron Mpro (P132H) in complex with demethylated analog of masitinib; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.88612877612 Å)