7TVS
The Crystal Structure of SARS-CoV-2 Omicron Mpro (P132H) in complex with demethylated analog of masitinib
Summary for 7TVS
Entry DOI | 10.2210/pdb7tvs/pdb |
Descriptor | 3C-like proteinase nsp5, N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)-4-[(piperazin-1-yl)methyl]benzamide, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | sars-cov-2, omicron, 3cl, masitinib, structural genomics, center for structural genomics of infectious diseases, csgid, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Severe acute respiratory syndrome coronavirus |
Total number of polymer chains | 1 |
Total formula weight | 34507.46 |
Authors | Tan, K.,Maltseva, N.I.,Endres, M.J.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2022-02-05, release date: 2022-02-16, Last modification date: 2023-10-18) |
Primary citation | Tan, K.,Maltseva, N.I.,Endres, M.J.,Joachimiak, A. The Crystal Structure of SARS-CoV-2 Omicron Mpro (P132H) in complex with demethylated analog of masitinib To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.88612877612 Å) |
Structure validation
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