7TUS
Sculpting a uniquely reactive cysteine residue for site-specific antibody conjugation
Summary for 7TUS
Entry DOI | 10.2210/pdb7tus/pdb |
Descriptor | Antibody Heavy Chain, Antibody Light Chain, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
Functional Keywords | antibody therapeutics, antibody-drug conjugate, catalytic antibody, protein modification, engineered cysteine, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 192963.24 |
Authors | |
Primary citation | Hwang, D.,Nilchan, N.,Park, H.,Roy, R.N.,Roush, W.R.,Rader, C. Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation. Bioconjug.Chem., 33:1192-1200, 2022 Cited by PubMed: 35584359DOI: 10.1021/acs.bioconjchem.2c00146 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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