7TGI

Single-domain VHH intrabodies neutralize ricin toxin

Summary for 7TGI

• Entry DOI: 10.2210/pdb7tgi/pdb
• Related: 7TGF
• Descriptor: Ricin chain A, VHH antibody, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: ricin toxin, vhh antibody, immune system, immune system-toxin complex, immune system/toxin
• Biological source: Ricinus communis (castor bean); More
• Total number of polymer chains: 2
• Total formula weight: 44820.35

Authors

Rudolph, M.J. (deposition date: 2022-01-07, release date: 2022-10-12, Last modification date: 2023-10-18)

• Primary citation: Czajka, T.F.,Vance, D.J.,Davis, S.,Rudolph, M.J.,Mantis, N.J.; Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins.; J.Biol.Chem., 298:101742-101742, 2022; PubMed: 35182523; DOI: 10.1016/j.jbc.2022.101742

Experimental method

X-RAY DIFFRACTION (2.104 Å)