7TFI

Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with an open clamp

7TFI の概要

• エントリーDOI: 10.2210/pdb7tfi/pdb
• EMDBエントリー: 25872 25873 25874 25875 25876
• 分子名称: Replication factor C subunit 1, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (11 entities in total)
• 機能のキーワード: dna replication, dna damage repair, rfc loader, pcna clamp, dna polymerase processivity factor, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast); 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 358410.78

構造登録者

Zheng, F.,Georgescu, R.,Yao, Y.N.,O'Donnell, M.E.,Li, H. (登録日: 2022-01-06, 公開日: 2022-11-16)

• 主引用文献: Zheng, F.,Georgescu, R.,Yao, N.Y.,Li, H.,O'Donnell, M.E.; Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.; Elife, 11:-, 2022; PubMed: 35829698; DOI: 10.7554/eLife.77469

実験手法

ELECTRON MICROSCOPY (3.41 Å)