7TF0

Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) spike protein in complex with human ACE2

Summary for 7TF0

Entry DOI	10.2210/pdb7tf0/pdb
EMDB information	25857
Descriptor	Spike glycoprotein, Processed angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	sars-cov-2, glycoprotein, fusion protein, viral protein, ace2
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	4
Total formula weight	511225.45
Authors	Zhu, X.,Saville, J.W.,Mannar, D.,Srivastava, S.S.,Berezuk, A.M.,Demers, J.P.,Zhou, S.,Tuttle, K.S.,Subramaniam, S. (deposition date: 2022-01-06, release date: 2022-03-30)
Primary citation	Saville, J.W.,Mannar, D.,Zhu, X.,Srivastava, S.S.,Berezuk, A.M.,Demers, J.P.,Zhou, S.,Tuttle, K.S.,Sekirov, I.,Kim, A.,Li, W.,Dimitrov, D.S.,Subramaniam, S. Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants. Nat Commun, 13:742-742, 2022 Cited by PubMed: 35136050 DOI: 10.1038/s41467-022-28324-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.02 Å)

Structure validation