7TDA

Crystal structure of the E. coli thiM riboswitch in complex with thiamine pyrophosphate, manganese ions

Summary for 7TDA

Entry DOI	10.2210/pdb7tda/pdb
Descriptor	thiM TPP riboswitch RNA (80-MER), THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	rna
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	27926.49
Authors	Nuthanakanti, A.,Serganov, A. (deposition date: 2021-12-30, release date: 2022-02-16, Last modification date: 2023-10-18)
Primary citation	Zeller, M.J.,Nuthanakanti, A.,Li, K.,Aube, J.,Serganov, A.,Weeks, K.M. Subsite Ligand Recognition and Cooperativity in the TPP Riboswitch: Implications for Fragment-Linking in RNA Ligand Discovery. Acs Chem.Biol., 17:438-448, 2022 Cited by PubMed: 35060698 DOI: 10.1021/acschembio.1c00880 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation