7TBB

Crystal structure of Plasmepsin X from Plasmodium falciparum

Summary for 7TBB

Entry DOI	10.2210/pdb7tbb/pdb
Descriptor	Plasmepsin 10, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... (5 entities in total)
Functional Keywords	aspartyl protease, hydrolase
Biological source	Plasmodium falciparum (malaria parasite P. falciparum)
Total number of polymer chains	1
Total formula weight	43734.18
Authors	Christensen, J.B.,Hodder, A.N.,Dietrich, M.H.,Scally, S.W.,Cowman, A.F. (deposition date: 2021-12-21, release date: 2022-05-04, Last modification date: 2023-10-18)
Primary citation	Hodder, A.N.,Christensen, J.,Scally, S.,Triglia, T.,Ngo, A.,Birkinshaw, R.W.,Bailey, B.,Favuzza, P.,Dietrich, M.H.,Tham, W.H.,Czabotar, P.E.,Lowes, K.,Guo, Z.,Murgolo, N.,Lera Ruiz, M.,McCauley, J.A.,Sleebs, B.E.,Olsen, D.,Cowman, A.F. Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax. Structure, 30:947-, 2022 Cited by PubMed: 35460613 DOI: 10.1016/j.str.2022.03.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation