7TAM

HRas G12V in complex with GDP

Summary for 7TAM

Entry DOI	10.2210/pdb7tam/pdb
Descriptor	GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	g-protein, hydrolase, signaling protein, globular protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	19449.16
Authors	Kouidmi, I.,Maddalena, M.,Laplante, S. (deposition date: 2021-12-21, release date: 2022-12-28, Last modification date: 2025-03-12)
Primary citation	Franca, T.C.C.,Maddalena, M.,Kouidmi, I.,Ayotte, Y.,Islam, S.T.,LaPlante, S.R. SI/II Pocket of Ras: An Opportunity for a Once "Undruggable" Target Acs Omega, 2025 Cited by DOI: 10.1021/acsomega.4c10493 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.87 Å)

Structure validation