7T7B
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab
Summary for 7T7B
Entry DOI | 10.2210/pdb7t7b/pdb |
Descriptor | Spike protein S1, ADI-62113 Fab heavy chain, ADI-62113 Fab light chain, ... (5 entities in total) |
Functional Keywords | cross-neutralizing antibody; yydrxg; sars-cov-2; adi-62113; sarbecovirus; pattern search; ighd3-22, immune system, immune system-viral protein complex, immune system/viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 3 |
Total formula weight | 72163.34 |
Authors | Liu, H.,Wilson, I.A. (deposition date: 2021-12-14, release date: 2022-08-03, Last modification date: 2023-10-18) |
Primary citation | Liu, H.,Kaku, C.I.,Song, G.,Yuan, M.,Andrabi, R.,Burton, D.R.,Walker, L.M.,Wilson, I.A. Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron. Commun Biol, 5:766-766, 2022 Cited by PubMed: 35906394DOI: 10.1038/s42003-022-03700-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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