7T7B
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Spike protein S1 | polymer | 205 | 23104.9 | 1 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 2 | H | ADI-62113 Fab heavy chain | polymer | 232 | 25165.2 | 1 | Homo sapiens (Human) | ||
| 3 | L | ADI-62113 Fab light chain | polymer | 214 | 23322.7 | 1 | Homo sapiens (Human) | ||
| 4 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 5 | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A: 333 - 530 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 531 | - | expression tag |
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
| His 536 | - | expression tag |
| His 537 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 71592.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 72163.3 |
