7SY7
Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417T mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)
This is a non-PDB format compatible entry.
Summary for 7SY7
Entry DOI | 10.2210/pdb7sy7/pdb |
EMDB information | 25519 |
Descriptor | Spike glycoprotein, Processed angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | sars-cov-2, glycoprotein, fusion protein, viral protein, ace2, viral protein-receptor complex, viral protein/receptor |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 4 |
Total formula weight | 511391.39 |
Authors | Zhu, X.,Mannar, D.,Saville, J.W.,Srivastava, S.S.,Berezuk, A.M.,Zhou, S.,Tuttle, K.S.,Kim, A.,Li, W.,Dimitrov, D.S.,Subramaniam, S. (deposition date: 2021-11-24, release date: 2021-12-29) |
Primary citation | Mannar, D.,Saville, J.W.,Zhu, X.,Srivastava, S.S.,Berezuk, A.M.,Zhou, S.,Tuttle, K.S.,Kim, A.,Li, W.,Dimitrov, D.S.,Subramaniam, S. Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding. Cell Rep, 37:110156-110156, 2021 Cited by PubMed: 34914928DOI: 10.1016/j.celrep.2021.110156 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.81 Å) |
Structure validation
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