7SXP

G-quadruplex structure formed in the NRAS mRNA with a G8U substitution

Summary for 7SXP

Entry DOI	10.2210/pdb7sxp/pdb
Descriptor	NRAS mRNA, POTASSIUM ION, CACODYLIC ACID (3 entities in total)
Functional Keywords	g-quadruplex, nras, rna
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	7635.61
Authors	Banco, M.T.,Ferre-D'Amare, A.R. (deposition date: 2021-11-24, release date: 2023-05-31, Last modification date: 2024-05-22)
Primary citation	Balaratnam, S.,Torrey, Z.R.,Calabrese, D.R.,Banco, M.T.,Yazdani, K.,Liang, X.,Fullenkamp, C.R.,Seshadri, S.,Holewinski, R.J.,Andresson, T.,Ferre-D'Amare, A.R.,Incarnato, D.,Schneekloth Jr., J.S. Investigating the NRAS 5' UTR as a target for small molecules. Cell Chem Biol, 30:643-657.e8, 2023 Cited by PubMed: 37257453 DOI: 10.1016/j.chembiol.2023.05.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation