7SXE

Crystal structure of ligase I with nick duplexes containing cognate G:T

Summary for 7SXE

• Entry DOI: 10.2210/pdb7sxe/pdb
• Descriptor: DNA ligase 1, DNA chain 1, DNA chain 2, ... (6 entities in total)
• Functional Keywords: ligase-dna complex, ligase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 85679.06

Authors

Tang, Q.,Gulkis, M.,McKenna, R.,Caglayan, M. (deposition date: 2021-11-22, release date: 2022-07-13, Last modification date: 2023-10-18)

• Primary citation: Tang, Q.,Gulkis, M.,McKenna, R.,Caglayan, M.; Structures of LIG1 that engage with mutagenic mismatches inserted by pol beta in base excision repair.; Nat Commun, 13:3860-3860, 2022; PubMed: 35790757; DOI: 10.1038/s41467-022-31585-w

Experimental method

X-RAY DIFFRACTION (3 Å)