7SX7
Crystal structure of broadly neutralizing antibody N49P9.3-FR3-3 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core
Summary for 7SX7
Entry DOI | 10.2210/pdb7sx7/pdb |
Descriptor | clade A/E 93TH057 HIV-1 gp120 core, N49P9.3-FR3-3 ANTIBODY FAB HEAVY CHAIN, N49P9.3-FR3-3 ANTIBODY FAB LIGHT CHAIN, ... (6 entities in total) |
Functional Keywords | hiv-1, vrc01-class antibody, cd4 binding site, clade a/e 93th057 gp120, viral protein-immune system complex, n49p9.3-fr3-3, immune system, immune system-viral protein complex, immune system/viral protein |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 6 |
Total formula weight | 178142.89 |
Authors | Tolbert, W.D.,Pazgier, M. (deposition date: 2021-11-22, release date: 2022-11-30, Last modification date: 2023-10-25) |
Primary citation | Tolbert, W.D.,Pazgier, M. Crystal structure of broadly neutralizing antibody N49P9.3-FR3-3 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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