7SUV
APE1 exonuclease substrate complex with 8oxoG opposite A
Summary for 7SUV
Entry DOI | 10.2210/pdb7suv/pdb |
Descriptor | DNA (5'-D(P*TP*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(8OG))-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... (5 entities in total) |
Functional Keywords | nuclease, dna repair protein, dna binding protein, hydrolase, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 75193.38 |
Authors | Whitaker, A.W.,Freudenthal, B.D. (deposition date: 2021-11-18, release date: 2022-09-07, Last modification date: 2023-10-18) |
Primary citation | Whitaker, A.M.,Stark, W.J.,Freudenthal, B.D. Processing oxidatively damaged bases at DNA strand breaks by APE1. Nucleic Acids Res., 50:9521-9533, 2022 Cited by PubMed: 36018803DOI: 10.1093/nar/gkac695 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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