7SUE

Crystal Structure of Human Fab S24-188 in the complex with the N-teminal Domain of Nucleocapsid protein from SARS CoV-2

7SUE の概要

• エントリーDOI: 10.2210/pdb7sue/pdb
• 分子名称: S24-188 Fab Light chain, S24-188 Fab Heavy chain, Nucleoprotein (3 entities in total)
• 機能のキーワード: sars coronavirus 2, nucleocapsid protein, human antibody fab, covid-19, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 247347.48

構造登録者

Kim, Y.,Maltseva, N.,Tesar, C.,Jedrzejczak, R.,Dugan, H.,Stamper, C.,Wilson, P.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2021-11-17, 公開日: 2022-08-10, 最終更新日: 2024-04-03)

• 主引用文献: Kim, Y.,Maltseva, N.,Tesar, C.,Jedrzejczak, R.,Endres, M.,Ma, H.,Dugan, H.L.,Stamper, C.T.,Chang, C.,Li, L.,Changrob, S.,Zheng, N.Y.,Huang, M.,Ramanathan, A.,Wilson, P.,Michalska, K.,Joachimiak, A.; Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.; Iscience, 27:108976-108976, 2024; PubMed: 38327783; DOI: 10.1016/j.isci.2024.108976

実験手法

X-RAY DIFFRACTION (2.9 Å)