7SSC
TRL345 lineage ancestor I8 Fab bound to an HCMV gB-derived peptide
Summary for 7SSC
Entry DOI | 10.2210/pdb7ssc/pdb |
Descriptor | TRL345-I8 Fab heavy chain, TRL345-I8 Fab light chain, Envelope glycoprotein B peptide, ... (5 entities in total) |
Functional Keywords | immunoglobulin, fusion protein, hcmv, immune system-viral protein complex, immune system/viral protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 48760.24 |
Authors | Sponholtz, M.R.,McLellan, J.S. (deposition date: 2021-11-10, release date: 2022-10-19, Last modification date: 2023-10-25) |
Primary citation | Jenks, J.A.,Amin, S.,Sponholtz, M.R.,Kumar, A.,Wrapp, D.,Venkatayogi, S.,Tu, J.J.,Karthigeyan, K.,Valencia, S.M.,Connors, M.,Harnois, M.J.,Hora, B.,Rochat, E.,McLellan, J.S.,Wiehe, K.,Permar, S.R. A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus. Plos Pathog., 19:e1011107-e1011107, 2023 Cited by PubMed: 36662906DOI: 10.1371/journal.ppat.1011107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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