7SQ1

BG505.MD39TS Env trimer in complex with Fab from antibody C05

7SQ1 の概要

• エントリーDOI: 10.2210/pdb7sq1/pdb
• EMDBエントリー: 25376
• 分子名称: Transmembrane protein gp41, Envelope glycoprotein gp160, C05 Fab Light chain, ... (9 entities in total)
• 機能のキーワード: antibody, env, envelope, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 282506.51

構造登録者

Moore, A.,Du, J.,Xu, Z.,Walker, S.,Kulp, D.W.,Pallesen, J. (登録日: 2021-11-04, 公開日: 2022-06-22, 最終更新日: 2022-12-07)

• 主引用文献: Xu, Z.,Walker, S.,Wise, M.C.,Chokkalingam, N.,Purwar, M.,Moore, A.,Tello-Ruiz, E.,Wu, Y.,Majumdar, S.,Konrath, K.M.,Kulkarni, A.,Tursi, N.J.,Zaidi, F.I.,Reuschel, E.L.,Patel, I.,Obeirne, A.,Du, J.,Schultheis, K.,Gites, L.,Smith, T.,Mendoza, J.,Broderick, K.E.,Humeau, L.,Pallesen, J.,Weiner, D.B.,Kulp, D.W.; Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer.; Nat Commun, 13:695-695, 2022; PubMed: 35121758; DOI: 10.1038/s41467-022-28363-z

実験手法

ELECTRON MICROSCOPY (3.8 Å)