7SN6

U2AF65 UHM BOUND TO SF3B155 ULM5

7SN6 の概要

• エントリーDOI: 10.2210/pdb7sn6/pdb
• 分子名称: Splicing factor U2AF 65 kDa subunit, Splicing factor 3B subunit 1, ISOPROPYL ALCOHOL, ... (4 entities in total)
• 機能のキーワード: u2af homology motif, uhm, pre-mrna splicing factor, protein binding, phosphorylation, protein-peptide complex, splicing, peptide binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 28498.31

構造登録者

Loerch, S.,Jenkins, J.L.,Kielkopf, C.L. (登録日: 2021-10-27, 公開日: 2022-07-27, 最終更新日: 2023-10-18)

• 主引用文献: Galardi, J.W.,Bela, V.N.,Jeffery, N.,He, X.,Glasser, E.,Loerch, S.,Jenkins, J.L.,Pulvino, M.J.,Boutz, P.L.,Kielkopf, C.L.; A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.; J.Biol.Chem., 298:102224-102224, 2022; PubMed: 35780835; DOI: 10.1016/j.jbc.2022.102224

実験手法

X-RAY DIFFRACTION (1.8 Å)