7SME

p107 pocket domain complexed with HDAC1 peptide

Summary for 7SME

Entry DOI	10.2210/pdb7sme/pdb
Descriptor	Retinoblastoma-like protein 1, Histone deacetylase 1, SULFATE ION, ... (4 entities in total)
Functional Keywords	transcription, cyclin box pocket transcriptional regulator, cell cycle
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	44657.36
Authors	Putta, S.,Fernandez, S.M.,Tripathi, S.M.,Muller, G.A.,Rubin, S.M. (deposition date: 2021-10-25, release date: 2022-06-29, Last modification date: 2023-10-18)
Primary citation	Putta, S.,Alvarez, L.,Ludtke, S.,Sehr, P.,Muller, G.A.,Fernandez, S.M.,Tripathi, S.,Lewis, J.,Gibson, T.J.,Chemes, L.B.,Rubin, S.M. Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family. Structure, 30:1340-, 2022 Cited by PubMed: 35716663 DOI: 10.1016/j.str.2022.05.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.64 Å)

Structure validation