7SJ2
N-acetylglucosamine-1-phosphotransferase (GNPT) alpha and beta subunits (GNPTAB) catalytic domain, from zebrafish, in complex with uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) and magnesium
7SJ2 の概要
エントリーDOI | 10.2210/pdb7sj2/pdb |
分子名称 | N-acetylglucosamine-1-phosphotransferase subunit alpha,N-acetylglucosamine-1-phosphotransferase (GNPT) alpha (GNPTAB) catalytic domain,N-acetylglucosamine-1-phosphotransferase subunit beta, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
機能のキーワード | gnpt, lysosome, mannose 6-phosphate, mucolipidosis, transferase |
由来する生物種 | Danio rerio (Zebrafish, Brachydanio rerio) 詳細 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 122008.71 |
構造登録者 | |
主引用文献 | Gorelik, A.,Illes, K.,Bui, K.H.,Nagar, B. Structures of the mannose-6-phosphate pathway enzyme, GlcNAc-1-phosphotransferase. Proc.Natl.Acad.Sci.USA, 119:e2203518119-e2203518119, 2022 Cited by PubMed: 35939698DOI: 10.1073/pnas.2203518119 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.3 Å) |
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