7SGL

DNA-PK complex of DNA end processing

7SGL の概要

• エントリーDOI: 10.2210/pdb7sgl/pdb
• EMDBエントリー: 25113
• 分子名称: DNA-dependent protein kinase catalytic subunit, X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, ... (9 entities in total)
• 機能のキーワード: endonuclease, kinase, complex, dna binding protein, transferase, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 737062.08

構造登録者

Liu, L.,Li, J.,Chen, X.,Yang, W.,Gellert, M. (登録日: 2021-10-06, 公開日: 2022-01-12, 最終更新日: 2022-01-19)

• 主引用文献: Liu, L.,Chen, X.,Li, J.,Wang, H.,Buehl, C.J.,Goff, N.J.,Meek, K.,Yang, W.,Gellert, M.; Autophosphorylation transforms DNA-PK from protecting to processing DNA ends.; Mol.Cell, 82:177-, 2022; PubMed: 34936881; DOI: 10.1016/j.molcel.2021.11.025

実験手法

ELECTRON MICROSCOPY (3 Å)