7SEN

Crystal structure of Fab containing a fluorescent noncanonical amino acid with blocked excited state proton transfer

Summary for 7SEN

Entry DOI	10.2210/pdb7sen/pdb
Descriptor	5c8* Fab heavy chain, 5c8* Fab light chain (3 entities in total)
Functional Keywords	fragment antigen binding (fab), noncanonical amino acid, 7-hydroxycoumarin, immune system
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	48002.38
Authors	Henderson, J.N.,Mills, J.H.,Simmons, C.R. (deposition date: 2021-09-30, release date: 2022-02-02, Last modification date: 2023-11-15)
Primary citation	Henderson, J.N.,Simmons, C.R.,Mills, J.H. Structural Basis for Blocked Excited State Proton Transfer in a Fluorescent, Photoacidic Non-Canonical Amino Acid-Containing Antibody Fragment. J.Mol.Biol., 434:167455-167455, 2022 Cited by PubMed: 35033559 DOI: 10.1016/j.jmb.2022.167455 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.09 Å)

Structure validation