7SEM

Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins

7SEM の概要

• エントリーDOI: 10.2210/pdb7sem/pdb
• 分子名称: MPE8 Fab heavy chain, Fusion glycoprotein F0, MPE8 Fab light chain, ... (5 entities in total)
• 機能のキーワード: human metapneumovirus, fusion protein, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 107779.10

構造登録者

Rush, S.A.,Hsieh, C.-L.,McLellan, J.S. (登録日: 2021-09-30, 公開日: 2022-02-16, 最終更新日: 2023-10-18)

• 主引用文献: Hsieh, C.L.,Rush, S.A.,Palomo, C.,Chou, C.W.,Pickens, W.,Mas, V.,McLellan, J.S.; Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.; Nat Commun, 13:1299-1299, 2022; PubMed: 35288548; DOI: 10.1038/s41467-022-28931-3

実験手法

X-RAY DIFFRACTION (2.2 Å)