7SE6
Crystal structure of human Fibrillarin in ligand-free state
Summary for 7SE6
Entry DOI | 10.2210/pdb7se6/pdb |
Descriptor | rRNA 2'-O-methyltransferase fibrillarin, FORMIC ACID (3 entities in total) |
Functional Keywords | methyltransferase, s-adenosyl methionine, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 26727.62 |
Authors | Shi, Y.,El-Deeb, I.M.,Masic, V.,Hartley-Tassell, L.,Maggioni, A.,von Itzstein, M.,Ve, T. (deposition date: 2021-09-30, release date: 2022-02-09, Last modification date: 2023-10-18) |
Primary citation | Shi, Y.,El-Deeb, I.M.,Masic, V.,Hartley-Tassell, L.,Maggioni, A.,Itzstein, M.V.,Ve, T. Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin. Pharmaceuticals, 15:-, 2021 Cited by PubMed: 35056083DOI: 10.3390/ph15010026 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
Download full validation report