7SCF
M. tb EgtD in complex with HD2
Summary for 7SCF
Entry DOI | 10.2210/pdb7scf/pdb |
Descriptor | Histidine N-alpha-methyltransferase, (2S)-3-(1H-imidazol-5-yl)-2-(1H-pyrrol-1-yl)propanoic acid, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
Functional Keywords | ergothioneine biosynthesis pathway, rossmann fold domain, histidine/histamine derivatives, sam dependent methyltransferase, transferase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 72489.36 |
Authors | Sudasinghe, T.D.,Ronning, D.R. (deposition date: 2021-09-28, release date: 2021-12-01, Last modification date: 2023-10-18) |
Primary citation | Sudasinghe, T.D.,Banco, M.T.,Ronning, D.R. Inhibitors of Mycobacterium tuberculosis EgtD target both substrate binding sites to limit hercynine production. Sci Rep, 11:22240-22240, 2021 Cited by PubMed: 34782676DOI: 10.1038/s41598-021-01526-6 PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report