7SA6
fHbp mutant 2416 bound to Fab JAR5
Summary for 7SA6
Entry DOI | 10.2210/pdb7sa6/pdb |
Descriptor | Factor H-binding protein 2416, JAR5 Heavy Chain, JAR5 Light Chain (3 entities in total) |
Functional Keywords | antigen, protein binding, immune system |
Biological source | Neisseria meningitidis serogroup B More |
Total number of polymer chains | 3 |
Total formula weight | 81011.62 |
Authors | Chesterman, C.,Malito, E.,Bottomley, M.J. (deposition date: 2021-09-22, release date: 2022-10-05, Last modification date: 2023-10-18) |
Primary citation | Chesterman, C.,Desautels, T.,Sierra, L.-J.,Arrildt, K.,Zemla, A.,Lau, E.Y.,Sundaram, S.,Laliberte, J.,Chen, L.,Ruby, A.,Mednikov, M.,Bertholet, S.,Yu, D.,Luisi, K.,Malito, E.,Mallett, C.,Bottomley, M.J.,Berg, R.,Faissol, D. Active Learning for Rapid Design: An iterative AI approach for accelerated vaccine design that combines active machine learning and high-throughput experimental evaluation To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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