7SA0

Crystal structure of CDK2 liganded with compound EF4195

Summary for 7SA0

• Entry DOI: 10.2210/pdb7sa0/pdb
• Descriptor: Cyclin-dependent kinase 2, 1,2-ETHANEDIOL, 2-{[(3R)-2,3,4,9-tetrahydro-1H-carbazol-3-yl]amino}-5-(trifluoromethyl)benzoic acid, ... (4 entities in total)
• Functional Keywords: allosteric inhibitor drug development kinase, cell cycle
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 34973.47

Authors

Sun, L.,Schonbrunn, E. (deposition date: 2021-09-21, release date: 2022-10-05, Last modification date: 2023-10-18)

• Primary citation: Sun, L.,Schonbrunn, E.; Development of selective allosteric inhibitors of cyclin-dependent kinase 2 (CDK2); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.59 Å)