7S9L
Crystal Structure of DNA Polymerase Beta with Ring open intermediate Fapy-dG base-paired with a dC
Summary for 7S9L
Entry DOI | 10.2210/pdb7s9l/pdb |
Descriptor | DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*(FAP)P*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*CP*AP*TP*GP*CP*GP*C)-3'), ... (7 entities in total) |
Functional Keywords | fapy-dg, polymerase beta, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 47913.91 |
Authors | Freudenthal, B.D.,Ryan, B.J. (deposition date: 2021-09-21, release date: 2022-08-03, Last modification date: 2023-10-18) |
Primary citation | Ryan, B.J.,Yang, H.,Bacurio, J.H.T.,Smith, M.R.,Basu, A.K.,Greenberg, M.M.,Freudenthal, B.D. Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication. J.Am.Chem.Soc., 144:8054-8065, 2022 Cited by PubMed: 35499923DOI: 10.1021/jacs.2c00193 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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