7S69

N-acetylglucosamine-1-phosphotransferase (GNPT) gamma subunit (GNPTG), from clawed frog

Summary for 7S69

• Entry DOI: 10.2210/pdb7s69/pdb
• Descriptor: N-acetylglucosamine-1-phosphotransferase gamma subunit, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: gnpt, mannose, mannose 6-phosphate receptor homology (mrh) domain, mucolipidosis, sugar binding protein
• Biological source: Xenopus laevis (African clawed frog)
• Total number of polymer chains: 2
• Total formula weight: 69811.79

Authors

Gorelik, A.,Illes, K.,Nagar, B. (deposition date: 2021-09-13, release date: 2022-05-25, Last modification date: 2023-10-18)

• Primary citation: Gorelik, A.,Illes, K.,Bui, K.H.,Nagar, B.; Structures of the mannose-6-phosphate pathway enzyme, GlcNAc-1-phosphotransferase.; Proc.Natl.Acad.Sci.USA, 119:e2203518119-e2203518119, 2022; PubMed: 35939698; DOI: 10.1073/pnas.2203518119

Experimental method

X-RAY DIFFRACTION (3.04 Å)