7S3T
NzeB Diketopiperazine Dimerase Mutant: Q68I-G87A-A89G-I90V
Summary for 7S3T
Entry DOI | 10.2210/pdb7s3t/pdb |
Descriptor | NascB, PROTOPORPHYRIN IX CONTAINING FE, (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, ... (6 entities in total) |
Functional Keywords | cytochrome p450, diketopiperazine dimerase, natural products, biosynthetic protein |
Biological source | Streptomyces sp. |
Total number of polymer chains | 1 |
Total formula weight | 45165.08 |
Authors | Harris, N.R.,Shende, V.V.,Sanders, J.N.,Newmister, S.A.,Khatri, Y.,Movassaghi, M.,Houk, K.N.,Sherman, D.H. (deposition date: 2021-09-08, release date: 2022-10-05, Last modification date: 2023-11-15) |
Primary citation | Shende, V.V.,Harris, N.R.,Sanders, J.N.,Newmister, S.A.,Khatri, Y.,Movassaghi, M.,Houk, K.N.,Sherman, D.H. Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases. Angew.Chem.Int.Ed.Engl., 2023 Cited by PubMed: 36610039DOI: 10.1002/anie.202210254 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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