7S3T
NzeB Diketopiperazine Dimerase Mutant: Q68I-G87A-A89G-I90V
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NascB | polymer | 401 | 43833.5 | 1 | UniProt (A0A3G1Q973) Pfam (PF00067) UniProt (by SIFTS) (A0A8I3B043) | Streptomyces sp. | |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C, D (A) | (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione | non-polymer | 283.3 | 2 | Chemie (QRP) | |||
| 4 | E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | H (A) | water | water | 18.0 | 367 | Chemie (HOH) |
Sequence modifications
A: 1 - 401 (UniProt: A0A3G1Q973)
| PDB | External Database | Details |
|---|---|---|
| Val 1 | Met 1 | conflict |
| Ile 68 | Gln 68 | engineered mutation |
| Ala 87 | Gly 87 | engineered mutation |
| Gly 89 | Ala 89 | engineered mutation |
| Val 90 | Ile 90 | engineered mutation |
| Gly 116 | Lys 116 | conflict |
| Asn 119 | His 119 | conflict |
| Asp 120 | Glu 120 | conflict |
| Leu 121 | Tyr 121 | conflict |
| Met 126 | Ile 126 | conflict |
| Ser 127 | Gly 127 | conflict |
| Ala 130 | Val 130 | conflict |
| Ser 131 | Asp 131 | conflict |
| Ala 140 | Arg 140 | conflict |
| Asp 141 | Glu 141 | conflict |
| Val 143 | Ala 143 | conflict |
| Leu 150 | Val 150 | conflict |
| Ser 160 | Thr 160 | conflict |
| Ala 161 | Ser 161 | conflict |
| Asp 165 | Ala 165 | conflict |
| Leu 166 | Arg 166 | conflict |
| Ala 168 | Val 168 | conflict |
| His 169 | Gly 169 | conflict |
| Cys 170 | Trp 170 | conflict |
| Val 180 | Ala 180 | conflict |
| His 187 | Arg 187 | conflict |
| Gln 191 | Glu 191 | conflict |
| Glu 194 | Arg 194 | conflict |
| Gly 205 | Ala 205 | conflict |
| Thr 206 | Gly 206 | conflict |
| Leu 214 | His 214 | conflict |
| Val 220 | Thr 220 | conflict |
| Asp 221 | Pro 221 | conflict |
| Gln 222 | Ala 222 | conflict |
| Gly 234 | Ala 234 | conflict |
| Ser 235 | Glu 235 | conflict |
| Leu 254 | Ile 254 | conflict |
| Asp 261 | Glu 261 | conflict |
| Ala 262 | Ser 262 | conflict |
| Ala 268 | Thr 268 | conflict |
| Glu 271 | Asp 271 | conflict |
| Tyr 283 | His 283 | conflict |
| Ser 287 | Ala 287 | conflict |
| Ser 290 | Ala 290 | conflict |
| Val 291 | Ala 291 | conflict |
| Ile 301 | Leu 301 | conflict |
| Lys 307 | Gly 307 | conflict |
| Leu 316 | Phe 316 | conflict |
| His 321 | Arg 321 | conflict |
| Val 331 | Arg 331 | conflict |
| Phe 350 | Thr 350 | conflict |
| Val 360 | Leu 360 | conflict |
| Arg 370 | Cys 370 | conflict |
| Arg 371 | His 371 | conflict |
| Ser 384 | Arg 384 | conflict |
| Ile 397 | Leu 397 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43833.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1331.6 | |
| All* | Total formula weight | 45165.1 |
